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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRKCI All Species: 50
Human Site: T412 Identified Species: 78.57
UniProt: P41743 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P41743 NP_002731.4 596 68262 T412 R P G D T T S T F C G T P N Y
Chimpanzee Pan troglodytes XP_001148501 597 67369 T415 G P G D T T S T F C G T P N Y
Rhesus Macaque Macaca mulatta XP_001089400 597 68263 T413 R P G D T T S T F C G T P N Y
Dog Lupus familis XP_535855 696 78257 T512 R P G D T T S T F C G T P N Y
Cat Felis silvestris
Mouse Mus musculus Q62074 595 68185 T411 R P G D T T S T F C G T P N Y
Rat Rattus norvegicus P09217 592 67715 T410 G P G D T T S T F C G T P N Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506164 360 41199 D199 E D Y G F S V D W W A L G V L
Chicken Gallus gallus XP_417561 606 69931 T424 G P G D T T S T F C G T P N Y
Frog Xenopus laevis NP_001084068 588 67442 T404 G P G D T T S T F C G T P N Y
Zebra Danio Brachydanio rerio Q90XF2 588 67303 T404 R P G D T T S T F C G T P N Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13678 634 71138 T461 M N G M L T T T F C G T P D Y
Honey Bee Apis mellifera XP_397273 590 68031 T405 R E G D T T A T F C G T P N Y
Nematode Worm Caenorhab. elegans Q19266 597 68017 T411 K D G D L T S T F C G T P N Y
Sea Urchin Strong. purpuratus XP_780275 524 59689 D363 E D Y D F S V D W W A L G V L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P87253 1142 127954 T976 W Y G S T T S T F C G T P E F
Conservation
Percent
Protein Identity: 100 66.6 96.8 84.3 N.A. 98.3 72.3 N.A. 59.9 71.4 89.7 88.7 N.A. 36.4 67.9 58.1 63.5
Protein Similarity: 100 78.5 97.4 84.9 N.A. 98.8 83.5 N.A. 60.4 83 94.4 92.9 N.A. 54 78.1 74.1 72.4
P-Site Identity: 100 93.3 100 100 N.A. 100 93.3 N.A. 0 93.3 93.3 100 N.A. 60 86.6 80 6.6
P-Site Similarity: 100 93.3 100 100 N.A. 100 93.3 N.A. 13.3 93.3 93.3 100 N.A. 73.3 93.3 86.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 23.9
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 35.7
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 66.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 7 0 0 0 14 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 87 0 0 0 0 0 % C
% Asp: 0 20 0 80 0 0 0 14 0 0 0 0 0 7 0 % D
% Glu: 14 7 0 0 0 0 0 0 0 0 0 0 0 7 0 % E
% Phe: 0 0 0 0 14 0 0 0 87 0 0 0 0 0 7 % F
% Gly: 27 0 87 7 0 0 0 0 0 0 87 0 14 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 14 0 0 0 0 0 0 14 0 0 14 % L
% Met: 7 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 0 0 0 0 0 0 0 0 74 0 % N
% Pro: 0 60 0 0 0 0 0 0 0 0 0 0 87 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 40 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 7 0 14 74 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 74 87 7 87 0 0 0 87 0 0 0 % T
% Val: 0 0 0 0 0 0 14 0 0 0 0 0 0 14 0 % V
% Trp: 7 0 0 0 0 0 0 0 14 14 0 0 0 0 0 % W
% Tyr: 0 7 14 0 0 0 0 0 0 0 0 0 0 0 80 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _